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The Journal of Pharmaceutical Chemistry is an online, open-access, peer-reviewed journal publishing high-impact research across the full spectrum of drug discovery and development. Following the tradition of leading publications like the Journal of Medicinal Chemistry, our scope emphasizes the crucial relationship between chemical structure and biological activity. We welcome the submission of original research articles, comprehensive reviews, short communications, and perspectives in areas including, but not limited to: the design and synthesis of novel therapeutic agents, structure-activity relationship (SAR) studies, computational chemistry and molecular modeling, pharmacology, pharmacokinetics, drug metabolism, and the chemistry of bioactive natural products. The journal aims to serve as a vital platform for both academic and industrial scientists, aiming to advance the translation of fundamental chemical and biological insights into new medicines.